Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester
Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester
CAS: 130219-46-4
Molecular Formula: C14H13NO2S
Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester - Names and Identifiers
| Name | Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester |
| Synonyms | Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester |
| CAS | 130219-46-4 |
Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester - Physico-chemical Properties
| Molecular Formula | C14H13NO2S |
| Molar Mass | 259.32 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Melting Point | 92-93 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) |
| Boling Point | 442.6±55.0 °C(Predicted) |
| pKa | 3.37±0.10(Predicted) |
Carbonothioic acid, S-(4-aminophenyl) O-(phenylmethyl) ester - Introduction
S-(4-Aminophenyl)-O-benzyl thiocarbonate, also known as ABTS(2,2 '-aminobis (3-ethylbenzothiazole)), is a commonly used chemical reagent with the following properties and uses.
Nature:
-Appearance: White or off-white crystalline powder.
-Molecular formula: C18H17N3O3S.
-Molecular weight: 359.41g/mol.
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and xylene, slightly soluble in water.
Use:
-Redox indicator: ABTS can be oxidized by oxidant oxygen or peroxide hydrogen to a stable cationic Radicalcation ABTS. ABTS has an absorption maximum of 734 nm, and the redox reaction can be monitored by measuring the amount of change in the absorption spectrum.
-Enzyme activity assay: ABTS is also commonly used to measure the activity of enzymes. One common application is to measure the activity of peroxidase.
Preparation Method:
The method for preparing S-(4-aminophenyl)-O-benzyl thiocarbonate is mainly synthesized by chemical reaction, and the specific steps are as follows:
1. react 4-aminobenzaldehyde with benzyl alcohol to generate 2-(benzyloxy) benzaldehyde.
2. The product obtained in step 1 is esterified with 2-hydroxybenzoic anhydride to obtain benzyl 2-(benzyloxy) benzoate.
3. The product obtained in step 2 is subjected to amination reaction with thiourea to generate S-(4-aminophenyl)-O-benzyl thiocarbonate.
Safety Information:
- ABTS is a chemical reagent that needs to follow normal laboratory practices and safety measures.
-Wear appropriate personal protective equipment, including lab coats, goggles and gloves.
-Avoid inhaling dust or contact with skin and eyes.
-Avoid ingestion and smoking during operation.
-Store in a dry, cool place away from fire and oxidizing agents.
Nature:
-Appearance: White or off-white crystalline powder.
-Molecular formula: C18H17N3O3S.
-Molecular weight: 359.41g/mol.
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and xylene, slightly soluble in water.
Use:
-Redox indicator: ABTS can be oxidized by oxidant oxygen or peroxide hydrogen to a stable cationic Radicalcation ABTS. ABTS has an absorption maximum of 734 nm, and the redox reaction can be monitored by measuring the amount of change in the absorption spectrum.
-Enzyme activity assay: ABTS is also commonly used to measure the activity of enzymes. One common application is to measure the activity of peroxidase.
Preparation Method:
The method for preparing S-(4-aminophenyl)-O-benzyl thiocarbonate is mainly synthesized by chemical reaction, and the specific steps are as follows:
1. react 4-aminobenzaldehyde with benzyl alcohol to generate 2-(benzyloxy) benzaldehyde.
2. The product obtained in step 1 is esterified with 2-hydroxybenzoic anhydride to obtain benzyl 2-(benzyloxy) benzoate.
3. The product obtained in step 2 is subjected to amination reaction with thiourea to generate S-(4-aminophenyl)-O-benzyl thiocarbonate.
Safety Information:
- ABTS is a chemical reagent that needs to follow normal laboratory practices and safety measures.
-Wear appropriate personal protective equipment, including lab coats, goggles and gloves.
-Avoid inhaling dust or contact with skin and eyes.
-Avoid ingestion and smoking during operation.
-Store in a dry, cool place away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
